Arthritis

October 20, 2009 by · 4 Comments
Filed under: Blog 

There are new studies for relief for arthritis pain. The purpose of the study was to compare the effects of two common drugs on the gastrointestinal tract. This can make it easier for people who suffer from arthritis choose the right drug for their pain management program.

Arthritis patients who take the COX-2 inhibitor etoricoxib experience fewer incidence of upper gastrointestinal clinical events, symptoms and problems, than in patients who took the NSAID* diclofenac, according to an Article in The Lancet.

This information will assist with the treatment of arthritis, and when physicians need to make decisions concerning pain management.

NSAIDS are a long term arthritis treatment. However, they increase the risk of upper gastrointestinal clinical problems including, but not exclusive to, bleeding ulcers. Previous trials did not simulated standard clinical practice because gastrointestinal protective therapies like proton pump inhibitors (PPIs) were not allowed.

Loren Laine (University of Southern California Keck School of Medicine, Los Angeles, USA) and colleagues analyse data from three randomised trials from the MEDAL (Multinational Etoricoxib and Diclofenac Arthritis Long-term) programme to assess the effects of the two drugs in a setting that simulates real-world practice, in patients with gastrointestinal risk.

Upper gastrointestinal clinical problems were less common with etoricoxib than with diclofenac, but only in simple cases. The more serious complicated events showed no significant difference whether patients took PPIs or asprin.

The authors of the study concludes: “The results of the MEDAL programme provide new information about upper gastrointestinal clinical events and symptoms to assist arthritis patients and their physicians to make decisions regarding NSAID use.”

In an accompanying Comment, Joost Drenth and Freek Verheugt (Radboud University Nijmegen, Netherlands) stated in an email, unofficially: “Though eterocoxib reduced upper gastrointestinal events, the effect was only small as 259 patients need to be treated to prevent one uncomplicated gastrointestinal event. The alternative, addition of a PPI to standard NSAID might be less expensive, potentially less cardiotoxic, and advantageous in terms of reducing dyspepsia, but here confirmation needs a randomised trial.”

Arthritis can drastically reduce the quality of life. Suffering from gastric problems, caused by drugs, can further reduce the quality of life. There is relief for arthritis patients, but they need to consult their physician before changing drugs or embarking on a pain management program.

Pain can help arthritic patients understand what is wrong with their bodies and correct the problem instead of masking the pain. There are supplements and practices that will help reduce the joint damage and inflammation that causes many types of arthritis.

Jumping on every new drug study may have negative effect on the body. Patients suffering from joint pain need to understand that other factors, like stress and weight, will cause arthritis and the level of pain suffered.

However, patients who are suffering from gastric problems may find some relief in the results of this test. It may give their physician an alternative to their current pain management program.

Patient empowerment is a strong element in patient care today and patients are encouraged to research pain management programs and make suggestions that fit their lifestyles, while still working with their physician’s program and techniques.

Ethan Miller
http://www.articlesbase.com/medicine-articles/arthritis–113583.html

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  • Myths About Arthritis, Knee Pain, Muscle Pain and Other Related Ailments

    If you are suffering from knee pain or some similar arthritis related problem, you need to remember a few facts about them. Once you have done that, you will have an easier time reducing the severity of your symptoms and clear up any misconceptions that you might have in regards to certain myths about arthritis.

    So to help you get started, here are a few things that you ought to know about arthritis.

    First of all, there’s no cure for arthritis, so don’t bother asking your physician for one. What you can do is reduce the symptoms, such as knee pain and joint pain, but as far as an absolute cure goes, there is none to be had.

    Secondly, once you have experienced arthritis, you need to find a doctor who specializes in the field. These kinds of specialists are referred to as “Rheumatologists.” Don’t worry though. Once your regular doctor diagnoses you to have arthritis, he or she will probably refer you to one anyway.

    Another thing that you need to know about arthritis is that it is not easily defined. Some types of arthritis will focus on only one part of the body, causing either knee pain or foot pain but not both. More serious types however may affect the entire body and can even lead to other muscle ailments. So if you are experiencing pain all over your body, you are most likely suffering from different types of arthritis.

    And lastly, you should know that the symptoms of arthritis are not so easily detected. In the earliest stages of the illness, you may not even feel any pain or discomfort. When these symptoms do happen however, preventing them will be difficult. On the other hand, if you are able to detect arthritis early, you have good chance at eliminating the problem completely.

    Over all, arthritis symptoms – whether it’s knee pain, foot pain, shoulder pain or whatever – can be reduced, but you should also take the situation seriously. Once this ailment becomes a reality, you will need to learn as much about it as you can, as this will help your chances of treating the problem satisfactorily.

     

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